Fosfo-Fos B (Ser27) Polyklonale Antilichaam, PerCP-Cy5,5 Vervoeging

The v-Fos oncogene was initially identified as the transforming gene of two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. The cellular homolog, c-Fos, encodes a nuclear phosphoprotein that is rapidly and transiently induced by a variety of agents and functions as a transcriptional regulator for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers which bind to specific DNA TPA response elements (TREs), c-Fos proteins are only active as heterodimers with members of the Jun gene family. Murine Fos B encodes a nuclear protein of 338 amino acids which has 70% homology with c-Fos, exhibits similar kinetics of expression as c-Fos and forms heterodimers with both c-Jun and Jun B which bind to TRE DNA response elements. Functional homologs of c-Fos and Fos B include Fra-1 and Fra-2 genes.

Fos B phospho S27; p-Fos B phospho S27; p-FosB phospho S27; FBJ murine osteosarcoma viral oncogene homolog B; FOS B; FOS-B; FBJ osteosarcoma oncogene B; FosB; G0/G1 switch regulatory protein 3; G0S3; GOS3; GOSB; MGC42291; Oncogene FOS B; Protein fosB; fosB; G0/G1 switch regulatory protein 3; G0S3; GOS 3; GOS B; GOSB; Oncogene FOS B; Oncogene FOSB; Protein fos B; DKFZp686C0818; FOSB_HUMAN.

2354

Ser27

Nucleus

Human

Phospho-Fos B (Ser27)

PerCP-Cy5.5

KLH conjugated synthetic phosphopeptide derived from human Fos B around the phosphorylation site of Ser27

WB, FCM

Purified by Protein A.

482nm/694nm

1µg/µl

WB (1:300-5000), FCM (1:20-100)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

2354

Mouse, Rat, Dog, Cow, Sheep, Horse, GuineaPig