Fosfo-IRS1 (Ser616) Polyklonale Antilichaam

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

IRS1 (phospho S616) ; p-IRS1 (phospho S616) ; HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS 1; IRS-1; IRS1; IRS1_HUMAN; OTTHUMP00000164234

3667

P35568

Ser616

Cytoplasm, Nucleus, Cell membrane

Human, Mouse, Rat

Phospho-IRS1 (Ser616)

Unconjugated

KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser616

WB, ELISA, FCM, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

3667

Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit