Fosfo-IRS1 (Ser616) Polyklonale Antilichaam, Biotine Vervoeging

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

IRS1 (phospho S616) ; p-IRS1 (phospho S616) ; HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS 1; IRS-1; IRS1; IRS1_HUMAN; OTTHUMP00000164234

3667

P35568

Ser616

Cytoplasm, Nucleus, Cell membrane

Human, Mouse, Rat

Phospho-IRS1 (Ser616)

Biotin

KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser616

WB, ELISA, IHC-P, IHC-F

Purified by Protein A.

1µg/µl

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C for 12 months.

3667

Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit