Fosfo-IRS1 (Ser616) Polyklonale Antilichaam, PE-vervoeging

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

IRS1 (phospho S616) ; p-IRS1 (phospho S616) ; HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS 1; IRS-1; IRS1; IRS1_HUMAN; OTTHUMP00000164234

3667

P35568

Ser616

Cytoplasm, Nucleus, Cell membrane

Human, Mouse, Rat

Phospho-IRS1 (Ser616)

PE

KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser616

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

496,564nm/578nm

1µg/µl

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

3667

Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit