Fosfo-IRS1 (Tyr1179) Polyklonale Antilichaam, PE-Cy5,5 Vermengd

May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.

IRS1 (phospho S1179) ; p-IRS1 (phospho S1179) ; p-IRS1; IRS1 (phospho-Ser1179) ; HIRS 1; HIRS1; Insulin Receptor Substrate 1; IRS-1; IRS 1; IRS1; OTTHUMP00000164234; IRS1_HUMAN.

3667

P35568

Tyr1179

Cell membrane

Human, Mouse, Zebrafish

Phospho-IRS1 (Tyr1179)

PE-Cy5.5

KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser1179.

FCM

Purified by Protein A.

488nm/694nm

1µg/µl

FCM (1:20-100)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

3667

Rat, Dog, Cow, Sheep, Pig, Chicken, Rabbit, GuineaPig