Fosfo-KCNJ1 (Ser44) Polyklonale Antilichaam, APC-Cy7 Vervoeging

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

KCNJ1 phospho S44; p-KCNJ1 phospho S44; KCNJ1 phospho Ser44; p-KCNJ1 Ser44; p-ROM-Kphospho S44; KCNJ1 phospho S25; p-KCNJ1 phospho S25; KCNJ1 phospho Ser25; p-KCNJ1 Ser25; p-ROM-Kphospho S25; ROM K; ROM-K; inwardly rectying subfamily J member 1; ATP regulated potassium channel ROM K; ATP sensitive inward rectier potassium channel 1; ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectier potassium channel 1; Inward rectier K+ channel Kir1.1; inwardly rectying K+ channel; IRK1_HUMAN; KCNJ 1; KCNJ; Kcnj1; Kir 1.1; Kir1.1; Potassium channel; Potassium channel inwardly rectying subfamily J member 1; potassium inwardly-rectying channel J1; ROMK 1; ROMK 2; ROMK; ROMK1; ROMK2.

Ser44

Cell membrane

Phospho-KCNJ1 (Ser44)

APC-Cy7

KLH conjugated synthetic phosphopeptide derived from human KCNJ1 around the phosphorylation site of Ser44

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/780nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Human, Mouse, Rat, Dog, Sheep, Horse