Fosfo-KIR5.1 (Ser416) Polyklonale Antilichaam, Cy5 Vervoeging

The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down?s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.

P-KIR5.1 phospho S416; 6430410F18Rik; AI132396; BIR9; Inward rectier K channel Kir5.1; Inward rectier K+ channel Kir5.1; Inward rectier potassium channel 16; IRK16; IRKG; KCNJ16; MGC33717; Potassium channel inwardly rectying subfamily J member 16; Potassium inwardly rectying channel subfamily J member 16; RP23-218O16.1; IRK16_HUMAN.

Ser416

Cell membrane

Phospho-KIR5.1 (Ser416)

Cy5

KLH conjugated synthetic phosphopeptide derived from human KIR5.1 around the phosphorylation site of Ser416

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

625,650nm/670nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit