Fosfo-MCM2 Antilichaam pS41

Acts as a component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. [UniProt]

Western blot: 1:500-1:2000

P49736

Human

A synthetic peptide from the sequence surrounding phosphorylated serine 41 of human MCM2 protein was used as the immunogen for the phospho-MCM2 antibody.

28M71

WB

Affinity chromatography

Purified

This phospho-MCM2 antibody is available for research use only.

Store the phospho-MCM2 antibody at -20°C.

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5 mg/mL BSA

Optimal dilution of the phospho-MCM2 antibody should be determined by the researcher.

Western blot testing of lysate from 1) human HeLa cells and 2) human HeLa cells treated with alkaline phosphatase, using phospho-MCM2 antibody.