Fosfo-PAK4/PAK5/PAK6-S474/S560/S602 Konijn mAb (AMR11993N)

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-PAK4/PAK5/PAK6-S474/S560/S602 Rabbit mAb (AMR11993N) .

10298/57144/56924

O96013 (PAK4-Antigen), Q9P286 (PAK5), Q9NQU5 (PAK6)

WB 1:500 - 1:2000

Liquid

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Calculated MW: 64, 80, 75 kDa Observed MW: 64KDa/75KDa

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10298/57144/56924

https://www.uniprot.org/uniprot/O96013(PAK4-Antigen),Q9P286(PAK5),Q9NQU5(PAK6)

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