Fosfo-SRC Familie-Y416 Konijn pAb (AMR00918N)

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-SRC Family-Y416 Rabbit pAb (AMR00918N) .

ASV; SRC1; THC6; c-SRC; p60-Src; SRC

2534/3055/3932/4067/6714/7525

P12931

Cell membrane, Cytoplasm, Mitochondrion inner membrane, Nucleus, cytoskeleton

WB (Human breast cancer, Human lung cancer cell, Mus musculus, Homo sapiens, Rattus norvegicus) IP (H460 and A549) IF (Mus musculus, Rattus norvegicus)

WB 1:500 - 1:2000

Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Calculated MW: 59kDa/60kDa Observed MW: 60KDa

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2534/3055/3932/4067/6714/7525

https://www.uniprot.org/uniprot/P12931

Email for sequence