Fosfo-STAT1 (Tyr701) Polyklonale Antilichaam, APC-Cy5,5 Vervoeging

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

STAT1Tyr701; signal transducers and activators of transcription 1; DKFZp686B04100; ISGF 3; Phosphorylated Stat1pTyr701; Signal transducer and activator of transcription 1 91kDa; Signal transducer and activator of transcription 1 alpha/beta; STAT 1; STAT 91; STAT91; Transcription factor ISGF 3 components p91 p84.

6772

Tyr701

Cytoplasm, Nucleus

Human, Mouse

Phospho-STAT1 (Tyr701)

APC-Cy5.5

KLH conjugated synthetic phosphopeptide derived from human STAT1 around the phosphorylation site of tyrosine 701

FCM

Purified by Protein A.

650nm/694nm

1µg/µl

FCM (1:20-100)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Phosphorylation

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

6772

Rat, Dog, Cow, Sheep, Pig, Rabbit