Fosfo-STAT3 (Tyr705) Polyklonale Antilichaam, PE-Cy5 Vermengd
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity) .
APRF; HIES; ADMIO; Signal transducer and activator of transcription 3; Acute-phase response factor; STAT3
6774
P40763
Tyr705
Cytoplasm, Nucleus
• Rabbit
Human, Mouse, Rat, Chicken
Phospho-STAT3 (Tyr705)
• Polyclonal
• IgG
PE-Cy5
KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Tyr705
WB, FCM
Purified by Protein A.
488nm/670nm
1µg/µl
WB (1:300-5000), FCM (1:20-100)
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Phosphorylation
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
6774
Beschrijving
Fosfo-STAT3 (Tyr705) Polyklonale Antilichaam, PE-Cy5 Vermengd Beschikbaar in 20 µL. Bestel eenvoudig online met snelle levering.
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