Fosfo-ULK1 (S556) antilichaam

ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200 kDa (FIP 200) (PMID:21460634) . ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC (PMID:23573318) .

Serine/threonine-protein kinase ULK1|Autophagy-related protein 1 homolog (ATG1, hATG1) |Unc-51-like kinase 1|ULK1|KIAA0722

8408

O75385

Human

Peptide

Phospho-ULK1 (S556) ULK1

Cardiovascular, Metabolism, Developmental biology, Signal Transduction

Immunogen affinity purified

WB: 1:500-1:2000

≥95% as determined by SDS-PAGE

Liquid

140-150 kDa

4°C with ice bag

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

WB

Peptide