Fostamatinib dinatrium
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Fostamatinib is a prodrug of the spleen tyrosine kinase inhibitor (Syk) R406 and is approved for the treatment of chronic immune thrombocytopenia. It has demonstrated significant reduction in inflammatory mediators such as TNFα, IL-1, IL-6, and IL-8 in arthritis models.1 Syk IC50 = 41 nM – Fostamatinib also inhibits Flt3, Lyn, and Lck with similar potency in vitro but displays higher selectivity Syk in cellular assays.2 Significantly inhibits LPS-induced inflammatory response via blocking STAT1/3 signaling.3 Fostamatinib restored myeloid homeostasis in severe COVID-19.4 Displayed synergistic effects with anti-PDL1 therapy against neuroblastoma.5 Fostamatinib induces metabolic reprogramming of acute myeloid leukemia stem cells.6
Unconjugated
White solid
-20°C
Beschrijving
Fostamatinib dinatrium Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
CYP707A2 Antibody
GTR17947107
2 mg
SsDNA Assay Kit
12645ES60
100 Tests
Eco Alu MTP (HxD) 6x7=42 plates 35mm, 223x630x135mm
TE15336
1 Piece
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
Cellubrevin Antibody
MBS9436639-01
0.05 mL
Oxidative Stress Combo Assay Tissue Kit
EA-7008
1 Each
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Recent gezochte producten
Recombinant Deinococcus radiodurans Protein RecA (recA)
MBS1071366-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein ApaG (apaG)
MBS1302345-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein grpE (grpE)
MBS1306645-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase obg (obg)
MBS1312662-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Era (era)
MBS1418228-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans GTPase Der (der)
MBS1445159-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Enolase (eno)
MBS1455279-01
0.05 mg (E-Coli)
Recombinant Deinococcus radiodurans Protein nrdI (nrdI)
MBS1483359-01
0.05 mg (E-Coli)