FOXA2 Antilichaam - middengebied HRP (ARP31944_P050-HRP)

Forkhead box A2

HNF3B, TCF3B, HNF-3-beta

3170

Q9Y261

NP_068556

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human FOXA2

FOXA2 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young.This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Two transcript variants encoding the same protein have been identified for this gene.

PPARGC1B; GSC; EN2; OTX2; ONECUT1; NCOA1; TLE1; MIP; HOXA5; LHX1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

FOXA2 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HepG2

0.5 mg/ml

Dog: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 77%; Rat: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

48kDa

Yang, G., (2008) Blood 111 (1), 392-401

Wet Ice

457

FOXA2

FOXA2

Rabbit

Hepatocyte nuclear factor 3-beta

NM_021784

ASQAQLGEAAGPASETPAGTESPHSSASPCQEHKRGGLGELKGTPAAALS