FOXG1 Antilichaam

FOXG1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain and plays an important role in the development of the brain and telencephalon (1) . It is essential for the proliferation of progenitor cells in the cerebral cortex and influences regional patterning in the mammalian telencephalon (2,3) . Expression is restricted to the neurons of the developing telencephalon (3) . The loss of FOXG1 results in an accelerated rate of neuronal differentiation and the shortening of the neurogenetic period in the embryonic cerebral cortex (2,4) .

2290

P55316

NP_005240

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Neuroscience, Stem Cell

FOXG1 antibody is affinity chromatography purified via peptide column.

Cat. No. 1463 - Rat Brain Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Chicken: (100%)

FOXG1 antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

FOXG1 antibody can be stored at 4˚ C, stable for up to one year.

IgG

FOXG1 antibody is human, mouse and rat reactive.

FOXG1

Forkhead box G1

Homo sapiens

Murphy DB, Wiese S, Burfeind P, et al. Human brain factor 1, a new member of the fork head gene family. Genomics 1994; 21:551-7.

Kumamoto T, Toma K, Gunadi, et al. Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013; 3:931-45.

Miyoshi G and Fishell G. Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron 2012;74:1045-58.

Mencarelli MA, Spanhol-Rosseto A, Artuso R, et al. Novel FOXG1 mutations associated with the congenital variant of Rett syndrome. J. Med. Genet. 2010; 47:49-53.

Forkhead box G1, Brain factor 1, Brain factor 2, BF1, BF2, FKH2, FKHL1, FKHL2, FKHL3, FKHL4, Forkhead box protein G1, FOXG1A, FOXG1B, FOXG1C, HBF-1, HBF2, HBF-3, HBF-G2, HFK1, HFK2, HFK3, KHL2, QIN

ELISA, WB, IF

32307177

Liquid