FOXH1 Antilichaam

FOXH1 Antibody: FOXH1 is a member of the Forkhead-box (FOX) family of transcription factors and is the human homolog of Xenopus forkhead activin signal transducer-1. FOXH1 plays an important role in mediating TGF-beta/activin signals through its interaction with the SMAD2-SMAD4 complex. It is expressed primarily during early development and localizes in the cytoplasm until it forms a complex with the SMAD proteins at which time it translocates to the nucleus to positively or negatively affect gene expression.

8928

O75593

NP_003914

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

FOXH1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1304 - Human Liver Tissue Lysate

1 mg/mL

FOXH1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

FOXH1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

40 kDa

IgG

FOXH1 antibody is predicted to not cross-react with any other members of the forkhead box family.

FOXH1

Cat. No. 10-201 - Human Liver Tissue Slide

Forkhead box H1

Homo sapiens

Chen X, Weisberg E, Fridmacher V, et al. Smad and FAST-1 in the assembly of activin-responsive factor. Nature 1997; 389:85-9.

Zhou S, Zewel L, Lengauer C, et al. Characterization of human FAST-1, a TGF beta and activin signal transducer. Mol. Cell 1998; 2:121-7.

Attisano L, Silvestri C, Izzi L, et al. The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signaling. Mol. Cell. Endocrinol. 2001; 180:3-11.

FOXH1 Antibody: FAST1, FAST-1, FAST1, FAST2, Forkhead box protein H1, Forkhead activin signal transducer 1, Fast-1

ELISA, WB, IF

4503657

Liquid