FOXN1 Antilichaam / Boorddooseiwit N1

FOXN1 is a member of the forkhead box (FOX) family of transcription factors, which play key roles in regulating gene expression. FOXN1 is primarily known for its critical function in the development and maintenance of the thymus, a crucial organ of the immune system. This protein is essential for the differentiation and maturation of thymic epithelial cells, which in turn support the development of T cells, a vital component of the adaptive immune response. Mutations in the FOXN1 gene have been linked to a rare genetic condition known as T-cell lymphopenia, where individuals have decreased levels of T cells and are more susceptible to infections. In addition to its role in immune function, FOXN1 has also been investigated for its potential in regenerative medicine. Studies have shown that FOXN1 expression is crucial for the regeneration of hair follicles and skin in mammals.

Western blot: 1:1000-1:2000

O15353

Human

A portion of amino acids 350-378 from the human protein was used as the immunogen for this FOXN1 antibody.

WB

Purified

This FOXN1 antibody is available for research use only.

Store at 4°C for up to one month. For long term, aliquot the FOXN1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting amounts. Titration of the FOXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot testing of human 1) A549 and 2) HeLa cell lysate with FOXN1 antibody. Predicted molecular weight ~69 kDa.