FOXO3 Antilichaam - N-terminalgebied: FITC (ARP38040_P050-FITC)

Forkhead box O3

FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2

2309

O43524

NP_001446

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit, Sheep, Zebrafish

The immunogen is a synthetic peptide directed towards the N terminal region of human FOXO3

FOXO3A belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia.This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

SMAD3; YWHAB; ERBB2IP; SIRT1; YWHAE; CDK6; AKT1; IKBKB; CHUK; CDT1; UBC; SKP2; MAPK1; PCNA; MDM2; BTRC; CREBBP; ELAVL1; SMAD4; MAPK6; NR1H3; NR1H2; NLK; VDR; SMAD1; EP300; STK4; FANCD2; RAD17; MYC; H2AFX; BRCA1; ATM; SIRT3; ATG101; YWHAH; PGK1; GBAS; FKBP

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 75%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

71kDa

Pew, T., (2008) Endocrinology 149 (5), 2637-2645

Wet Ice

673

FOXO3

FOXO3

Rabbit

Forkhead box protein O3

NM_001455

MAEAPASPAPLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGE