FOXO4 Antilichaam - C-terminaal gebied: Biotine (ARP32110_P050-Biotine)

Forkhead box O4

AFX, AFX1, MLLT7

4303

P98177

NP_005929

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse

The immunogen is a synthetic peptide directed towards the C terminal region of human FOXO4

FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.

REL; SFN; AKT1; OGT; UBC; ATXN3; MDM2; NLK; USP7; CTNNB1; CREBBP; VDR; SIRT1; SMAD3; XPO1; YWHAZ; SMAD4; FOXG1; AKT2; ESR1; PIN1; CCND1; CDKN1A

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

54kDa

Wet Ice

505

FOXO4

FOXO4

Rabbit

Forkhead box protein O4

NM_005938

TPVLTPPTEAASQDRMPQDLDLDMYMENLECDMDNIISDLMDEGEGLDFN