
FP-20 (natrium)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
FP-20 sodium, a selective TLR4 agonist, is a vaccine adjuvant. FP-20 sodium induces MAPK- and NLRP3-dependent inflammasome activation. FP20 shows no toxicity in mouse vaccination experiments with OVA antigen and induces IgG production[1].
3056013-47-6
12352005
Toll-like Receptor (TLR)
Immunology/Inflammation
Inflammation/Immunology
CCCCCCCCCCCC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC(CCCCCCCCCCC)=O)CO)OP(O)(O[Na])=O)OC(CCCCCCCCCCC)=O)=O
C42H79NNaO11P
828.04
[1]Alessio Romerio, et al. New Glucosamine-Based TLR4 Agonists: Design, Synthesis, Mechanism of Action, and In Vivo Activity as Vaccine Adjuvants. J Med Chem. 2023 Feb 23;66 (4) :3010-3029.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N16024/
Natural Products
No Development Reported
Beschrijving
FP-20 sodium, a selective TLR4 agonist, is a vaccine adjuvant. FP-20 sodium induces MAPK- and NLRP3-dependent inflammasome activation. FP20 shows no toxicity in
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