FRα-targeting peptide C7 (TFA)

FRα-targeting peptide C7 TFA is a selective peptide ligand for folate receptor α (FRα) that has specific binding to FRα expressing cells and in vivo tumor targeting ability. FRα-targeting peptide C7 TFA can be used in the research of tumor diagnosis and treatment[1].

12352209

Antifolate

Cell Cycle/DNA Damage

Cancer-programmed cell death

Cancer

99.73

DMSO : 100 mg/mL (ultrasonic)

O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CC3=CNC4=CC=CC=C34)C(NCC(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N.OC(C(F)(F)F)=O.[x]

C62H90N18O16S.xC2HF3O2

1375.55 (free base)

[1]Junxing Li, et al. Identification of a peptide for folate receptor alpha by phage display and its tumor targeting activity in ovary cancer xenograft[J]. Scientific reports, 2018, 8 (1) : 8426.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10501A/FRα-targeting-peptide-C7-TFA-SDS-MedChemExpress.pdf

Peptides

No Development Reported