FRS3 Antilichaam - middengebied: Biotine (ARP52228 P050-Biotine)

Fibroblast growth factor receptor substrate 3

SNT2, FRS2B, SNT-2, FRS2beta, FRS2-beta

10817

O43559

NP_006644

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human FRS3

FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

NOTCH2NL; RFX6; SPERT; ADAMTSL4; SH3KBP1; CD2AP; SPRY2; TRIP6; TCF4; PLSCR1; GATA1; ERBB2; CBL; AES; ELAVL1; RND1; KARS; BMPR2; NTRK2; PRKCI; NTRK1; MAPK1; PTPN11; FGFR1; GRB2

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

54kDa

Huang, L., (2006) Oncogene 25 (49), 6457-6466

Wet Ice

492

FRS3

FRS3

Rabbit

Fibroblast growth factor receptor substrate 3

NM_006653

GFPDGEEDETPLQKPTSTRAAIRSHGSFPVPLTRRRGSPRVFNFDFRRPG