Fructose-fenylalanine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Fructose-phenylalanine (Fru-Phe) is a non-competitive angiotensin-converting enzyme (ACE) inhibitor (IC50 =0.19 mM) with antioxidant activities. Fructose-phenylalanine forms a stable complex with Zn2+ ions at the ACE active site, blocking the conversion of angiotensin I to II and thereby lowering blood pressure. Fructose-phenylalanine is promising for research of cardiovascular diseases[1][2].
31105-03-0
Fru-Phe
12352005
H302-H315-H319-H335
Angiotensin-converting Enzyme (ACE)
Metabolic Enzyme/Protease
Cardiovascular Disease
OC[C@@H](O)[C@@H](O)[C@H](O)C(CN[C@H](C(O)=O)CC1=CC=CC=C1)=O
C15H21NO7
327.33
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
[1]Johnson GH, et al. Nutritional implications of the Maillard reaction: the availability of fructose-phenylalanine to the chick. J Nutr. 1977 Sep;107 (9) :1659-64.|[2]Jiahao Yu, et al. Potential contribution of Amadori compounds to antioxidant and angiotensin I converting enzyme inhibitory activities of raw and black garlic. LWT, Volume 129, 2020, 109553, ISSN 0023-6438
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W585934/
Reference compound2
No Development Reported
Beschrijving
Fructose-phenylalanine (Fru-Phe) is a non-competitive angiotensin-converting enzyme (ACE) inhibitor (IC50 =0.19 mM) with antioxidant activities. Fructose-phenyl
Specificaties
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