FSCN1 Antilichaam

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.

6624

Q16658

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 260-380 of human FSCN1 (NP_003079.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 55kDa

IgG

FSCN1

HeLa

U-251MG

Mouse brain

Rat brain

Fascin

Homo sapiens

Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1, FAN1, HSN, SNL

WB, IHC

Liquid