FST-eiwit (C-human IgG1-Fc, menselijk)

FST

FS

C-human IgG1-Fc

< 1.0 EU per μg of the protein as determined by the LAL method

> 85 % as determined by SDS-PAGE

1. Measured by its ability to bind human INHBA-his in a functional ELISA. 2. Measured by its ability to bind mouse INHBA-his in a functional ELISA. 3. Measured by its ability to neutralize Activin-mediated inhibition on MPC11 cell proliferation. The ED50 for this effect is typically 0.5-3 μg/mL in the presence of 10 ng/ml Recombinant Human ctivin A.

Met1-Trp344

The secreted recombinant human FST/Fc is a disulfide-linked homodimer. The reduced monomer consists of 556 amino acids and has a predicted molecular mass of 61.7 kDa. As a result of glycosylation, rh FST/Fc monomer migrates as an approximately 70 kDa band in SDS-PAGE under reducing conditions.

Human