FTH1 Antilichaam - middengebied: Biotine (ARP54620_P050-Biotine)

Ferritin, heavy polypeptide 1

FHC, FTH, HFE5, PLIF, FTHL6, PIG15

2495

P02794

NP_002023

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the middle region of human FTH1

FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

SDCBP; FTL; FTH1; WDYHV1; CEP57; AURKB; TP53; AURKA; ASB15; ASB16; SUPT16H; SET; MAPK9; MAX; IGSF8; TICAM2; HCVgp1; PIAS4; CDC16; YWHAE; SOX5; MYL3; LBP; KPNA2; GRB2; DAXX; CSNK2B; CDC25A; ATP6V1B1; CD99; SPP1; TRAF4; SUMO2; UBC; Cep55; Trim28; NR1I3; NR3

Biotin

Polyclonal Antibody

IHC, WB

Affinity Purified

FTH1 is supported by BioGPS gene expression data to be expressed in HeLa

0.5 mg/ml

Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

21kDa

Sammarco, M.C., (2008) J. Biol. Chem. 283 (8), 4578-4587

Wet Ice

183

FTH1

FTH1

Rabbit

Ferritin heavy chain

NM_002032

NVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKM