FTO Antilichaam - middengebied: Biotine (ARP47474 P050-Biotine)

Fat mass and obesity associated

GDFD, ALKBH9, BMIQ14

79068

Q9C0B1

NP_001073901

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human FTO

The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.

UBC; SUMO1; NEDD8; BCCIP; CNDP2; DAK; NDRG1; NPEPPS; SLC9A3R1; CTSA; PEPD; MVD; LDHB; LDHA; EEF2; CKB

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 86%; Guinea Pig: 100%; Horse: 79%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 93%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

58kDa

Wet Ice

505

FTO

FTO

Rabbit

Alpha-ketoglutarate-dependent dioxygenase FTO

NM_001080432

WWCQPMAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLTA