FTS/AKTIP Polyklonale Antilichaam, FITC-vervoeging

Component of the FTS/Hook/FHIP complex (FHF complex) . The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex) . Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.

FT1; FTS; AKT-interacting protein; Fused toes protein homolog; AKTIP

64400

Q9H8T0

Cytoplasm, Cell membrane

Mouse

201-292/292

FTS/AKTIP

FITC

KLH conjugated synthetic peptide derived from human FTS/AKTIP

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

494nm/518nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

64400

Human, Rat, Dog, Cow, Sheep, Pig, Horse