FUT6 Polyklonale Antilichaam, APC-Cy5.5 Vervoeging

Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which is an essential interface for biological recognition processes. Fucosyltransferases catalyze the covalent association of fucose to different positional linkages in sugar acceptor molecules. The carbohydrate moieties generated and covalently attached to cell surfaces are necessary to ensure a surface contour that satisfies physiological roles, which are reliant on adhesion molecules such as Selectins (1-3) . Hematopoietic lineages rely on Fucosyltransferases to confer a surface carbohydrate phenotype, which mediates proper cell adhesion molecule recruitment and cell trafficking (4-6) .

Alpha 1,3 fucosyltransferase; EC=2.4.1.65; FCT3A; Fuc TVI; Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase; FUT6_HUMAN.

2528

Cytoplasm, Cell membrane

101-200/359

FUT6

APC-Cy5.5

KLH conjugated synthetic peptide derived from human FUT6/FucT-VI

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/694nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

2528

Human