FXN / Frataxin Antibody, KO gevalideerd

This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

2395

Q16595

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin (NP_000135.2) .

Unconjugated

Primary Antibodies

Antibody is Knockout validated.

Signal Transduction

Affinity purification

K-562

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 14kDa

IgG

WB: 1:500 - 1:2000

FXN

U-87MG

Jurkat

Raji

DU-145

Mouse kidney

Frataxin, mitochondrial

Homo sapiens

Frataxin, mitochondrial, Friedreich ataxia protein, Fxn, Frataxin intermediate form, i-FXN, Frataxin (56-210), m56-FXN, Frataxin (78-210), d-FXN, m78-FXN, Frataxin mature form, Frataxin (81-210), m81-FXN, FXN, FRDA, X25

WB

Liquid