FXYD5 Antilichaam - N-terminaal gebied: Biotine (ARP37690_T100-Biotine)

FXYD domain containing ion transport regulator 5

RIC, IWU1, KCT1, OIT2, DYSAD, HSPC113, PRO6241

53827

Q96DB9

NP_659003

Human, Mouse, Yeast

The immunogen is a synthetic peptide directed towards the N terminal region of human FXYD5

FXYD5 is a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. Mouse FXYD5 has been termed RIon Channel (Related to Ion Channel) . FXYD2, also known as the gamma subunit of the Na, K-ATPase, regulates the properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIon Channel) have been shown to induce channel activity in experimental expression systems. Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. This gene product, FXYD5, has not been characterized as a protein.

UBC

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Human: 100%; Mouse: 100%; Yeast: 90%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

20kDa

Batistatou, A., et al., (2005) Br. J. Cancer 93 (12), 1382-1387

Wet Ice

178

FXYD5

FXYD5

Rabbit

FXYD domain-containing ion transport regulator 5

NM_144779

LQPTSPTPTWPADETPQPQTQTQQLEGTDGPLVTDPETHKSTKAAHPTDD