G3BP Antilichaam

Ras-GTPase-activating protein SH3-domain-binding protein; GAP binding protein; RasGAP-associated endoribonuclease G3BP. This protein is one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

10146

Q13283

NP_005745.1

Human, Mouse, Rat

132-350

Unconjugated

Primary Antibodies

Signal Transduction

Antigen affinity-purified

1 mg/mL

Phosphate-Buffered Saline. No preservatives added.

None

Blue Ice

G3BP antibody can be stored at 4˚ C for short term (weeks) . Long term storage should be at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

52.2 kDa (calculated)

G3BP (M-219) antibody can be used for the detection of G3BP (M-219) by Western blot, may also work for IHC and ICC.

G3BP1

GTPase activating protein (SH3 domain) binding protein 1

Homo sapiens

Parker, F., Maurier, F., Delumeau, I., Duchesne, M., Faucher, D., Debussche, L., Dugue, A., Schweighoffer, F., Tocque, B. A Ras-GTPase-activating protein SH3-domain-binding protein. Molec. Cell. Biol. 16: 2561-2569, 1996.

G3BP, Ras GTPase-activating protein-binding protein 1, ATP-dependent DNA helicase VIII, G3BP-1, G3BP, HDH-VIII, G3BP (M219)

WB

5031703

Liquid