G6PD Antilichaam - middengebied: Biotine (ARP58469_P050-Biotine)

Glucose-6-phosphate dehydrogenase

G6PD1

2539

P11413

NP_000393

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

The immunogen is a synthetic peptide directed towards the middle region of human G6PD

G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.

G6PD; SUMO2; UBC; MDM2; CKB; CAPN1; ALDH7A1; ZNF622; ZFYVE19; UBFD1; CNDP2; ISOC1; MAT2B; ERP44; YWHAQ; SLC9A3R1; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; EIF4H; VCL; UBE2V1; TGM2; PPP1R2; PGD; PAK2; LDHB; SFN; GNS; GLA; GBP2; EIF5; BAG3; FN1; CCT4; HARS; SUMO4

Biotin

Polyclonal Antibody

WB

Affinity Purified

G6PD is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 85%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 86%; Sheep: 83%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

57kDa

Langbein, S., (2008) Int. J. Cancer 122 (11), 2422-2428

Wet Ice

515

G6PD

G6PD

Rabbit

Glucose-6-phosphate 1-dehydrogenase

NM_000402

VTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRI