GABRD Antilichaam

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.

2563

O14764

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 330-430 of human GABRD (NP_000806.2) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 68kDa

IgG

WB: 1:500 - 1:2000

GABRD

Mouse brain

Rat brain

Rat liver

Gamma-aminobutyric acid (GABA) A receptor, delta

Homo sapiens

GABRD, MGC45284, EJM7, EIG10, GEFSP5

WB

Liquid