GAD2 Antilichaam

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

2572

Q05329

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 401-585 of human GAD2 (NP_001127838.1) .

Unconjugated

Primary Antibodies

Cancer, Neuroscience

Affinity purification

HeLa

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 70kDa

IgG

GAD2

U-87MG

Glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Homo sapiens

GAD2, GAD65, glutamate decarboxylase 2 (pancreatic islets and brain, 65 kDa), Glutamate decarboxylase-2 (pancreas), 65kD)

WB, IHC, IF

Liquid