GADD45A Mouse Monoclonal Antibody [Kloon ID: LBI2B7]

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]

Carrier-free (BSA/glycerol-free) GADD45A mouse monoclonal antibody, clone LBI2B7

DDIT1; GADD45

Homo sapiens growth arrest and DNA damage inducible alpha (GADD45A), transcript variant 1, mRNA.

1647

P24522

Unconjugated

Cell cycle, MAPK signaling pathway, p53 signaling pathway

Cell cycle, MAPK signaling pathway, p53 signaling pathway

WB 1:4000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

GADD45A

https://www.ncbi.nlm.nih.gov/gene/?term=1647

https://www.uniprot.org/uniprot/P24522