GALNAC4S-6ST Antilichaam - middelste regio : HRP (ARP47193 P050-HRP)

Carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

BRAG, GALNAC4S-6ST

51363

Q7LFX5

NP_056976

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

The immunogen is a synthetic peptide directed towards the middle region of human GALNAC4S-6ST

GALNAC4S-6ST is a sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc (4,6-SO (4) ) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc (4SO4) -GlcA (2SO4) -GalNAc (6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. GALNAC4S-6ST may also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression; however such results are unclear in vivo.

UBC; RRAGD; LYN; HCK

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

CHST15 is supported by BioGPS gene expression data to be expressed in MCF7

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

65kDa

Sawada, T., (2005) Carbohydr. Res. 340 (12), 1983-1996

Wet Ice

561

CHST15

CHST15

Rabbit

Carbohydrate sulfotransferase 15

NM_015892

YDNSTDGEPPFLTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKS