GAPDH-antilichaam12D5]

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. It also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1) . GAPDH also plays a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease (2) . GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

2597

P04406

NP_002037

Human, Mouse, Rat

GAPDH antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GAPDH.

12D3D5

Unconjugated

Primary Antibodies

Signal Transduction, Neuroscience, Homeostasis

GAPDH antibody is Protein A purified.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/mL

GAPDH antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

GAPDH antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

GAPDH antibody is human, mouse, and rat reactive.

GAPDH

Glyceraldehyde-3-phosphate dehydrogenase

Homo sapiens

Sirover MA. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J. Cell. Biochem. 2005; 95:45-52.

Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu. Rev. Pharmacol. Toxicol. 2005; 45:269-90.

Glyceraldehyde-3-phosphate dehydrogenase, G3PDH, GAPD

ELISA, WB

7669492

Liquid