GCAT Antilichaam

The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

23464

O75600

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 170-419 of human GCAT (NP_055106.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Mouse eye

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45kDa

IgG

WB: 1:500 - 1:2000

GCAT

2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial

Homo sapiens

2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase, GCAT, KBL

WB

Liquid