GCLM Antilichaam / Glutamate-Cysteine Ligase Regulatory Subunit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.
Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-50, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25
P48507
• Rabbit
Human, Mouse
A portion of amino acids 246-274 from the human protein were used as the immunogen for the GCLM antibody.
• Polyclonal
• Ig
WB, IHC-P, FACS, IF
Antigen affinity purified
Purified
This GCLM antibody is available for research use only.
Aliquot the GCLM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
In 1X PBS, pH 7.4, with 0.09% sodium azide
The stated application concentrations are suggested starting points. Titration of the GCLM antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Cytoplasmic
Western blot testing of human HeLa cell lysate with GCLM antibody. Predicted molecular weight ~31 kDa.
Beschrijving
GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy cataly
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