GCP-2 (CXCL6)

GCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert anti-angiogenic activity. Human GCP-2 is cross-react on murine cells. Recombinant human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.

CXCL6; GCP2; CKA-3; GCP-2; SCYB6

6372

P80163

NP_002984.2

NM_002993.4

4q21

Human

Hamster, Monkey, Rat, Human, Bacteria

VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGKQVCL DPEAPFLKKV IQKILDSGNK KN

< 0.1 ng/µg of protein (< 1EU/µg)

> 98% by SDS-PAGE & HPLC analyses

Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.

72

Lyophilized

7.9 kDa

E. coli