GCSH Antilichaam

Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase) . The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH) . Two transcript variants, one protein-coding and the other probably not protein-coding, have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.

2653

P23434

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human GCSH (NP_004474.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

LO2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 19kDa

IgG

WB: 1:500 - 1:2000

GCSH

293T

HeLa

Mouse kidney

Rat liver

Glycine cleavage system H protein, mitochondrial

Homo sapiens

Glycine cleavage system H protein, mitochondrial, Lipoic acid-containing protein, GCSH

WB

Liquid