GDC-2992
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2753651-10-2
RO7656594
C04929-1mg
Androgen Receptor
Endocrinology & Hormones
C45H51ClN8O5
GDC-2992 (RO7656594, Compound 28A) is an orally active degrader of androgen receptor (AR) with a DC50 of 2.7 nM. It binds to AR and cereblon (CRBN), inducing AR ubiquitination and degradation. GDC-2992 also inhibits cell proliferation in VCaP cells and exhibits potential to reduce treatment resistance and disease relapse in prostate cancer.
Beschrijving
GDC-2992 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
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