GDF1 Antilichaam

GDF1 Antibody: Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. GDF1 was initially identified as a temporally expressed gene in the mouse central nervous system during embryonic development, with only one isoform detected in adult tissues. GDF1 is required for left-right patterning during development and directly interacts with Nodal, another member of the TGF-beta superfamily. It has been suggested that GDF1 regulates the activity and signaling range of Nodal through direct interaction.

2657

P27539

NP_001483

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Stem Cell

GDF1 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1462 - Rat Lung Tissue Lysate

1 mg/mL

GDF1 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

GDF1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

41 kDa

IgG

GDF1 antibody is predicted to not cross-react with any other members of the growth differentiation factor family.

GDF1

Cat. No. 10-101 - Human Lung Tissue Slide

Growth differentiation factor 1

Homo sapiens

Massague J. 1990. The transforming growth factor-beta family. Ann. Rev. Cell Biol. 6:597-641.

Lee SJ. Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure. Proc. Natl. Acad. Sci. USA 1991; 88:4250-4.

Rankin CT, Bunton T, Lawler AM, et al. Regulation of left-right patterning in mice by growth/differentiation factor-1. Nat. Genet. 2000; 24:262-5.

Tanaka C, Sakuma R, Nakamura T, et al. Long-range action of Nodal requires interaction with GDF1. Genes Dev. 2007; 21:3272-82.

GDF1 Antibody: RAI, DORV, DTGA3GDF-1

ELISA, WB, IF

110349792

Liquid