GDF5 Antilichaam

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat, teeth, and the growth of neuronal axons and dendrites. Mutations in this gene are associated with acromesomelic dysplasia, brachydactyly, chondrodysplasia, multiple synostoses syndrome, proximal symphalangism, and susceptibility to osteoarthritis.

8200

P43026

Mouse, Rat

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human GDF5 (NP_000548.2) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction, Stem Cell

Affinity purification

Mouse heart

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45kDa

IgG

GDF5

Rat heart

Growth differentiation factor 5

Homo sapiens

GDF5, CDMP-1, CDMP1, GDF-5, LAP4, Radotermin, OS5, BMP14, SYNS2

WB, IHC

Liquid