GED 0507-34-Levo
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
GED 0507-34-Levo is an orally active PPARγ modulator. GED 0507-34-Levo downregulates the expression of TGF-β, Smad3, IL-13, and CTGF in the colon. GED 0507-34-Levo improves DSS-induced chronic colitis and fibrosis[1].
921195-93-9
12352005
H315-H319-H335
Interleukin Related; PPAR; TGF-beta/Smad
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Stem Cell/Wnt; TGF-beta/Smad; Vitamin D Related/Nuclear Receptor
Inflammation/Immunology
O=C(O)[C@@H](OC)CC1=CC=C(N)C=C1
C10H13NO3
195.22
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
[1]Speca S, et al. Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis. Inflamm Bowel Dis. 2016 Feb;22 (2) :279-92.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W109107/
Reference compound1
No Development Reported
IL-13; PPARγ
Beschrijving
GED 0507-34-Levo is an orally active PPARγ modulator. GED 0507-34-Levo downregulates the expression of TGF-β, Smad3, IL-13, and CTGF in the colon. GED 0507-34-L
Specificaties
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