Gehydrolyseerde humane HLA-A*01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Proteïne (Monomer, MALS geverifieerd)

The HLA-A*01:01 allele is a prevalent human MHC class I variant, and its peptide-binding specificity determines the immune response in individuals carrying this allele. MAGEA3 is a member of the Melanoma-Associated Antigen family, characterized by its restricted expression in normal tissues (primarily testes and placenta) but frequent re-expression in various tumors, such as melanoma, lung cancer, and others.

The HLA-A*01:01 allele is a prevalent human MHC class I variant, and its peptide-binding specificity determines the immune response in individuals carrying this allele. MAGEA3 is a member of the Melanoma-Associated Antigen family, characterized by its restricted expression in normal tissues (primarily testes and placenta) but frequent re-expression in various tumors, such as melanoma, lung cancer, and others.

Biotinylated Human HLA-A*01:01&B2M&MAGEA3 (EVDPIGHLY) Complex Protein is produced by co-expression of HLA-A*01:01 and B2M loaded with MAGEA3 peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 36.0 kDa and 13.8 kDa. The protein migrates as 40-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Gly 25-Thr 305 (HLA-A*01:01) & Ile 21 - Met 119 (B2M) & EVDPIGHLY

HLA-A*0101 & B2M & MAGEA3 (EVDPIGHLY)

Biotin-labeled

C-10xHis & C-Avi

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

1.0 EU per μg

90%

Powder

PBS, pH7.4

36.0 kDa and 13.8 kDa

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RT

-20°C

25ug*1

HEK293

Human

Q5SUL5 (HLA-A*01:01) & P61769-1 (B2M) & EVDPIGHLY

Trehalose