
Gevokizumab ELISA Kit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Gevokizumab (XOMA-052) was developed by XOMA Ltd., USA and represents a humanized IgG2kappa antibody. XOMA-052 binds to IL-1β with high affinity leading to reduced binding affinity of the cytokine to its signaling receptor. Since gevokizumab does not influence the affinity of IL-1β for its decoy and soluble inhibitory receptors the endogenous regulatory mechanisms involving the clearance and inhibitory receptors also contribute to the effect of the antibody [6]. In August 2012 the FDA granted orphan drug status to gevokizumab for the treatment of noninfectious intermediate uveitis, posterior uveitis, panuveitis, and chronic noninfectious anterior uveitis. A single intravenous injection of the substance was also shown to lead to complete resolution of intraocular inflammation in Behçet’s uveitis.
Gevokizumab
XOMA 052, CAS: 1129435-60-4
Colorimetric
Quantitative
Plasma, Serum
0.31-5 μg/mL
80-120%
0.156 μg/ml
2-8 °C
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
For Research Use Only.
Beschrijving
Gevokizumab ELISA Kit Beschikbaar in 96 Tests. Bestel eenvoudig online met snelle levering.
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