Girdin (fosfo Ser1417) Antilichaam

Girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.

55704

Q3V6T2

NP_060554.3

Human, Mouse

Girdin (phospho Ser1417) antibody was raised against a peptide sequence around phosphorylation site of Serine 417 (L-E-M (p) -A-Q) derived from Human Girdin .

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

216 kDa

IgG

The antibody detects endogenous levels of Girdin only when phosphorylated at serine 1417.

CCDC88A

Coiled-coil domain containing 88A

Homo sapiens

Enomoto A., Dev. Cell 9:389-402 (2005) .

Simpson F., Traffic 6:442-458 (2005) .

Hillier L.W., Nature 434:724-731 (2005) .

APE, GIV, GRDN, HkRP1, KIAA1212

IHC

50897852

Liquid